Nutrients in Seabuckthorn Seed Oil:

1.      A Discussion on Pharmacological Standards for Seabuckthorn Seed Oil.

Seabuckthorn seed oil is higher level vitamin E and b-carotene than other oils.

 Zhang Rao, Ye Yongqing, Shu Meiying. A Discussion on Pharmacological Standards for Seabuckthorn Seed Oil. HIPPOPHAE. 1989, Vol.4 : 41-43.

2.      Lab report on Rich Nature Seabuckthorn Seed Oil:

            Total vitamin E (d-a-tocopheryl-sccinate):    307mg/100g (279IU/100g)

                     d-a-Tocopherol (most active form):    256mg/100g (233IU/100g)

  Data in Rich Nature Lab. 1998.

Anti-inflammatory:

3.      A Clinic Observation: Seabuckthorn Seed Oil Treatment of Reflex Esophagitis.

Forty patients were diagnosed Esophgitis by pathology laboratory.  Thirty-four were males and six were females. 3-5 ml (0.96mg/ml) of seabuckthorn seed oil were given to patients 3 times per day.  The average treatment lasted 14 months. The effective rate was 97%.  Seabuckthorn seed oil protected the mucous of stomach and inhibited the growth of H. pylori.

 Li Changshun, Chang Xinmin, Wang Fenrong, et al. from First Teaching Hospital of Xian Medical University. A Clinic Observation: Seabuckthorn Seed Oil Treatment of Reflex Esophagitis. HIPPOPHAE. 1996, Vol.9 (4): 40-41.

4.      Medical Applications of Seabuckthorn.

Seabuckthorn oil’s anti-inflammatory properties were widely recognized.   It was used to treat Laryngopharyngitis, stomach ulcer, etc.  In 1959, a Russia doctor reported that after 34 to 47 days of treatment of seabuckthorn oil, most symptoms caused by stomach ulcer were relieved.

A rat study in Russia showed seabuckthorn oil reduced stomach ulcer induced by Resurpine…

Seabuckthorn oil were found to inhibit variety bacteria, including Staphylococcus, Streptococcus, Typhoid bacillus, E.coli, and Bacillus dysenteriae…

A Chinese doctor, Dr. Gao used seabuckthorn seed oil to treat 100 cases of burn patients.  He applied the seed oil locally and the average recovery was about one week.

In 1952, the Ministry of Public Health of Soviet Union approved the topical application of seabuckthorn oil as a alternative for burn treatment.

Zhou Pengyuan, Jiang li. A Clinic Observation: Seabuckthorn Seed Oil Treatment of Reflex Esophagitis. HIPPOPHAE. 1995, Vol.8 (1): 20-25.

5.      Anti Radiation Inflammation Effects from Seabuckthorn Seed Oil and Fruit Oil.

Radiation inflammation on mice were induced in the study. Then researchers administered seabuckthorn seed oil and seabuckthorn fruit juice to mice.  The result demonstrated that seabuckthorn oil increase the survival rate by 30-35%.

Cheng Tijuan, Zhu Yuzhen, et al. Anti Radiation Inflammation Effects from Seabuckthorn Seed Oil and Fruit Oil. HIPPHAE.  1995, Vol.8(4): 32-35.

6.      A Report on 32 Cases of Burn Patients Treated by Seabuckthorn Seed Oil.

Thirty two cases of burn patients were treated only by seabuckthorn seed oil.  Doctors applied sterilized oil on the wounds.  The average recover was about 5-7 weeks.

Zhao Yisheng from Airforce Xian Hospital. A Report on 32 Cases of Burn Patients Treated by Seabuckthorn Seed Oil.  HIPPOHAE.  1994, Vol. 7 (3): 36-37.

7.      Data from Rich Nature Lab.

A lab test was done on seabuckthorn berry oil.  Modest inhibition of 15-lipoxygenase and Cyclooxygenase was observed.  Cyclooxygenase produces prostaglandins, which are markers of inflammation.  From lab result, we anticipate anti-inflammatory agents are present.

Letter from Seattle Biomed. Feb. 21th. 1995.

8.      Prevention Magazine: Special Report, Read It Here First: The Next Herbal Superstars

Seabuckthorn (Hippophae rhamnoides) oil is commonly applied to the skin in Russia and China to reduce inflammation, relieve pain, promote tissue regeneration, and reduce age-induced skin wrinking. 

… the herb is worth a try…

Varro E. Tyler, PhD, ScD.  HerbNews. Special Report, Read It Here First: The Next Herbal Superstars Prevention. May, 1999. 108-109.

Improving Cholesterol Profile:

1.      Medical Application of Seabuckthorn Oil

A clinical study in Huaxi Medical University reported seabuckthorn oil improved lipid profile for hyperlipemia patients.  Seabuckthorn oil were given to patients for 1-3 months at the dosage of 12ml/day.  The decrease of cholesterol and triglyceride were observed.

Flavonoid isolated from seabuckthorn was studied by Dr. Zhang Peiyun, et al.  Total cholesterol reduced from 238±79mg% to 180±36mg% in 77 patients and  HDL increase to 86.8±28mg% from 56.5±13mg% in 30 cases (P<0.001). Triglyceride decreased to 125±99mg% from 200±183mg% in 52 patients (P<0.001).

Russia doctors gave patients 15g/day of seabuckthorn oil.  The reduction of cholesterol and triglyceride were observed in most patients after 30 days.

Zhou Pengyuan, Jiang li.  HIPPOPHAE. 1995, Vol.8 (1): 20-25.

2.      Medical Research and Development on Seabuckthorn.

Flavonoids isolated from seabuckthorn has anti-angina properties. A double blind control study conducted by Dr. Zhang Maoliang from Huaxi Medical University showed flavonoids can slightly relieve angina.  Flavonoids in seabuckthorn may increase the coronary blood flow and inhibit platelet aggregation.

Xu Mingyu, Sun Xiaoxuan, Tong Wenxin. Medical Research and Development on Seabuckthorn.  HIPPOPHAE. 1994, Vol.7 (1): 32-39.

Anti-mutation and immune system studies:

1.       Observation: Anti-mutation and Anti immune-suppresser Properties from Seabuckthorn Seed Oil.

The micronucleus test of mice showed that seabuckthorn seed oil reduced micronucleus induced by Cyclophosphane. 

Ren Lifeng, Yang Jianping, et al. Observation: Anti-mutation and Anti immune-suppresser Properties from Seabuckthorn Seed Oil.  HIPPOPHAE. 1992, Vol.5.

2.      Anti-cancer Studies from Russia.

One study in Russia showed that extract from seabuckthorn had anti-cancer properties.  Three hundred eighty  mice (hermaphroditism) and ninety normal mice with induced Lewis lung cancer were studied.  The result demonstrated that seabuckthorn strengthened immune system, increase the activity of NK cells and interleukin I.

Zhang Zhemin, Qiu Deming. Anti-cancer Studies from Russia. HIPPOPHAE.  1995, Vol.8 (4):38-40.

Toxicity studies:

1.      Toxicity Studies on Seabuckthorn Seed Oil

LD50 of Force feeding seabuckthorn seed oil to mice was >60mg/kg.  A long term toxicity study showed no abnormal in blood, kidney and liver function and no pathological change in heart, lung, liver, kidney, adrenal gland and sex organs after 3 months of force feeding at dosage of 2ml/kg, 5ml/kg and 10ml/kg.

Che Xiping, Guan Xiaohong, et al. Toxicity Studies on Seabuckthorn Seed Oil. HIPPOPHAE. 1996, Vol.9 (1): 38-41.

2.      Medical Research and Development on Seabuckthorn.

Shannxi Pharmacological Research Institute carried a long term toxicity study on rats.  Rats were forced feeding 18g/kg ( almost 20 times of clinical dosage ) of seabuckthorn oil and no toxicity effect were found.

Xu Mingyu, Sun Xiaoxuan, Tong Wenxin. Medical Research and Development on Seabuckthorn.  HIPPOPHAE. 1994, Vol.7 (1): 32-39.

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